Timolol Maleate

 NIVON SPECIALTIES (INDIA)

 

Nivon Specialties (India) specializes in marketing wide range of Latest Active Pharmaceutical Ingredients API, sourcing new molecules, Formulation, Custom Synthesis, Contract manufacturing, Pharma Intermediates , Dossier/DMF preparation to the worldwide market, manufactured in GMP approved plants.

We offer from W.H.O. G.M.P. manufacturing facilities matching International standards. Our policy of strict adherence to demanding delivery schedules is complemented with high degree of innovation, high quality products and excellent service.

We are very strong in the following APIs and its formulations and can support you with DMF / Dossiers , Manufacturing License (Form 25 and Form 28) / WHO GMP Certificate / Free Sales Certificate /FDA Product Permission / COPP / ISO / COA

We also have BA/BE studies ready for 55 products and more are to be added shortly

Alendronate,  Adapalene, Atorvastatin, Amlodipine , Ambroxol,  Amodiaquine, Ambazone, Allantoin, Ascorbyl palmitate, AmylMetaCresol, Allopurinol, Atenolol, Artemether,Bromhexine, Bifonazole, Budesonide, Betamethasone, Cefexime, Cetirizine, Carvedilol, Cyproheptadiene,  Clopidogrel, Cefuroxime, Cyclandelate, Cetrimide, Cilostazol, Capecitabine, Calcitriol, Chlorzoxazone, Cinitapride, Domperidone, Desloratadine, Doxylamine, Dorzolamide, Diacerein , Donepezil, Diphenhydramine, Doxazosin, Esomeprazole, Eprosartan,  Ezetimibe, Erythromycin, Ebastine, Ethopabate, Fluticasone, Fluconazole, Fexofenadine, Furosemide, Formoterol,  Fenoprofen, Felodipine, Fosinopril, Fluocinolone, Glibenclamide,  Gemcitabine, Glimepiride, Granisetron, Glipizide, Glycopyrrolate, Glucosamine,Gefitinib, Galantamine, Halquinol, Hydralazine, Itopride, Itraconazole, Isoxsuprine, Ibuprofen, Isosorbide, Ivermectin, Irbesartan, Ipratropium ,  Irinotecan , Imatinib , Ketoconazole, Loperamide , Lansoprazole, Lisinopril. Lamotrigine, Loratadine, Losartan, Levosalbutamol, lercanidipine, Levocetirizine, Lumefantrine, Lacosamide , Latanoprost‏,  lenalidomide, Lovastatin, Meloxicam,  Mometasone, Montelukast, Mebeverine, Metoprolol , Miconazole, Moxifloxacin,  Methocarbamol,  Metoclopramide, Mebendazole, Metformin, Mefenamic,  Nebivolol, Niclosamide,  Nevirapine, Nateglinide, Nalidixic, Orlistat, Omeprazole, Ondansetron, Ornidazole, Oxyclozanide, Olmesartan, Pioglitazone,  Pantoprazole, Pregabalin, Phenylepherine, Pamidronate, Perindopril, Prasugrel, Piroxicam, Proguanil, Quinine, Ramipril, Rabeprazole, Rosiglitazone, Rosuvastatin,  Rafoxanide, Rizatriptan, Sildenafil,  Salbutamol, Salmeterol, Sumatriptan,  Simvastatin, Sodium Cromoglycate,  Simethicone , Solifenacin,  Sitagliptin, Terbinafine, Trimetazidine  Triprolidine, Tadalafil,  Timolol , Trioxsalen,  Tamsulosin, Telmisartan, Tamoxifen, Trandolapril, Tazarotene, Tenoxicam,  Temozolomide, Tolnaftate, Tinidazole, Terbutaline, Triamcinolone, Voriconazole, Valsartan, Valacyclovir, Vinblastine, Vincristine, Vardenafil, Warfarin, 

Amlodipine Intermediate ( Phthaloyl Amlodipine )

Bromo Compound ( 2-Acetoxy-5-(2-Bromoacetyl)-1-Benzylacetate) / Bromobenzene

1-Benzyl-4-Piperidone (Pharma Intermediate)

Bromhexine HCL Intermediate (2-Aminobenzoic Acid Methyl Ester (CAS 134-20-3)

Clopidogrel sulfate intermediates.

Chelating Agent : (p-Toluenesulfonic acid (PTSA) / p-Toluenesulfonyl Chloride (TOSYL

                          CHLORIDE) /  Ethyl Para Toulene Sulfonate.)

Carvedilol Intermediate :  (CAS 51997-51-4 /  CAS 1836-62-0  )

Domperidone Intermediate ( N Carbethoxy-4-Piperidone /  Domperidone Base)

Eprosartan ( Thiophene-2-Aldehyde)

Fexofenadine Intermediate (CAS NO: 154477-55-1 )

Fluconazole Intermediate.

Formoterol Intermediates (Benzyl Formoterol / CAS# 43229-01-2 / CAS# 43229-65-8 )

Imatinib Intermediate ( N-(2-Methyl-5-aminophenyl)-4-(3-Pyridyl)-2-Pyrimidine /   

                                    4-(4-methyl-1-piperazinyl)methyl benzoic acid dihydrochloride )

Isoxsuprine Hcl Intermediate (4- Hydroxy Propiophenone / 4- Benzyloxy  

                         Propiophenone / 4’-Benzyloxy-2-Bromo-Propiophenone.)

Gefitinib Intermediate

Loratadine Intermediate ( Methyl Loratadine / 8-Chloro-5,6-dihydro-11H-             

                                         benzo[5,6]cyclohepta[1,2-b]pyridin-11-one

Lamotrigine Intermediate (Schiff Base, DCBN, 2,3 Dichloro Benzoyl Nitrile)

Lansoprazole Intermediates

Losartan Intermediate (Trityl Losartan )

N Methyl-4-piperidone & Piperdione derivatives

Mono Chloro Acetic Acid 99% min

Microcrystalline Cellulose PH 101

Montelukast Intermediates

Methyl Iodide

Miconazole Base

Nebivolol  Intermediate ( 6 Fluorocarboxylic  Acid)

N,N,DiethylBenzamide (Mosquito repellent)

Pioglitazone Intermediates (5-Ethyl Pyridine-2-Ethanol /  2,4-Thiazolidinedione)

Piperazine Citrate

Rabeprazole Intermediate (  2-Mercapto Benzimidazole / 2,3-dimethyl-4-nitropyridine N-oxide /

                                             Methyl Mercapto Benzimidazole,2Mercapto-5-

                                             MethoxyBenzimidazole)

Ritodrine Hcl  ( 1-(4-Benzyloxyphenyl)-2-(4-hydroxy phenethylamino) Propanone HCL )

Salmeterol Xinafoate Intermediate: 4-Phenyl-1-Butanol /4-(6-Bromohexyloxy)butylbenzen/N- 

                                          Benzyl-6-(4 Benzyl butoxy) hexylamine./  1-phenylpiperazine /             

                                          Salmeterol Base).

Salbutamol Intermediate (Salbutamol Base, O-Benzyl Salbutamol )

Sildenafil Intermediate (4-Amino-1-methyl-3-propylpyrazole-5-carboxamide HCL )

Strontium Ranelate

Stannous Oxide / Stannic Oxide/Stannous Sulphate

Tributyl tin oxide  / Dibutyl tin oxide

Telmisartan Intermediate : (Methyl 4(bromomethyl) (1,1biphenyl)-2-Carboxylate] .

Triethyl Amine Hcl ( Pharma Intermediate)

Timolol  Maleate Intermediate : (3-Chloro-4-Morpholino-1,2,5-Thiadiazole / Tosyl Chloride /        

                                                    PTSA, Timolol Base )

Alendronate Sodium 70 mg / Atorvastatin  Calcium 10 mg  /  Albendazole Tabs / Ascorbic acid tab( vitamin c) Chewable / Amoxicillin 250 mg + combinations / Azithromycin / Atenolol tabs / Amlodipine Besilate Tabs / Artemether Syr. 300mg\100ml /  Ceftriaxone 250mg  & 1000 mg Inj  /  Cefuroxime susp , vial /  Cefotaxime 125mg & 1000 mg Inj./ Ciprofloxacin Tabs / Carvedilol Tabs /  Clopidogrel Bisulphate tabs / Clarithromycin tab /   Desloratadine Tabs / Drotaverin 40 mg /  Dapoxetine 60 mg tab / Dextrose 5% + Sodium Chloride 0.18% /Fluconazole caps /  Glucosamin HCL 500mg + Chondroitin sulphate 400mg  /  Granisetron Inj Isotretinoin Capsules / Metformin 500 mg  + Gliclazide 80 mg /  Multivitamin + mineral + amino acids tabs  / Moxifloxacin 400 mg / Orlistat 120 mg caps / ORS (oral rehydration solutions/salts) / Omeprazole 20 mg caps  / Pantoprazole 40 mg /  Pioglitazone 15/30/45 mg./ Paclitaxel inj / Sildenafil 100/150 mg tabs / sildenafil 100mg + Dapoxetine 60mg /  Sildenafil Jelly / Tadalafil 20 mg/40 mg  tabs / Tadalafil 20mg + Dapoxetin 60 mg /  Trimetazidine 35 mg tabs / Vardenafil 20 mg tabs + Dapoxetine 60 mg

We have following dossiers in CTD format ready and can also make on your required products with timelines.

We also have UKMHRA formulation unit form where we can supply finished formulation.

CTD list

1.Levofloxacin tab 250 mg/500 mg/750 mg.

2.Azithromycin tab 250 mg/500 mg.

3.Esomeprazole cap 20 mg.

BA/BE list

1.Rosuvastatin 20 mg tab

2.Trimetazidine MR 35 mg tab

3.Cotrimoxazole 400 mg tab

4.Clopidogrel 75 mg tab

5.Cetrizine 10 mg cap

6.Attorvastatin 10 mg tab

7.Lansoprazole delayed release 30 mg cap

 

(For compiled & Complete list , check our website www.nivonindia.com)

Dioxidine,Nifuratel,Potassium orotate,Nitrazol,Miramistin,Mebhydrolin napadisylate,Luminol sodium,N-Acridone acetic acid, Chinoxidine

Impurity / Reference standards / working standards can be provided

 

 

All freelancers / Indenting agents/ Commission  agents are requested to contact us, we will cover their interest and will also provide customer protection agreement

 

Reactions which can be carried  at  Dombivali  Plant:

 

Fridel craft reactions/ Cyclizations / Condensations / Saponification /Oxidation /Esterfication/High Vacuum Distillation/Amidation

 

a) Products protected by valid patents  are not offered for sale in countries where  the sale of such products constitutes a patent infringement  and its liability is at buyers risk.

b) Products currently covered by valid U.S patents. are offered for R & D use in accordance with 35 USC 271(e) + A13( 1)

c) Product list is covered under “Bolar Provision” and only non commercial samples for R & D are available.

 

 

DEEPAK KHANNA (CEO)

 

 

M/s Nivon Specialties (India)

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(API's, Pharma Int., New Molecules,Formulation & Custom Synthesis)

(Established Since 1999 in Mumbai & Reg. with Trademark Authorities)

Vashi, Navi Mumbai, Maharashtra.

Mobile : 009323789882

Tel : 0091-22-27825365

Fax : 0091-22-27824698
email : nivonpharma@yahoo.com

Hotmail: deepakkhanna938@hotmail.com

Website: www.nivonindia.com